Subhash Kulkarni, PhD.

Principal Investigator

Assistant Professor of Medicine

 

I received my PhD in Life Sciences from the University of Lausanne in Switzerland, and went on to do my post-doctoral training at Stanford University, first working on Evolutionary Genetics and then into Neurogastroenterology.

 

Since moving to Johns Hopkins, my research has been focused on understanding the origin and development of the enteric nervous system (ENS) and its maintenance in adults. The seminal contribution of my lab working together with a team of collaborators has been to show the presence of a rapid and a robust mechanism of neurogenesis in the adult gut, that maintains neuronal populations to conserve gastrointestinal function. My lab in collaboration with other labs at JHU and beyond is studying the biotic and abiotic factors that maintain ENS structure and the mechanisms by which the ENS connects and cross-talks with other gastrointestinal cells.

CURRENT LAB MEMBERS

Ken Hui, MD PhD

Research Fellow 

I am a clinical research fellow working on understanding the vagal afferent innervation of the gastrointestinal tract. Using a combination of high-resolution microscopy and transcriptomic analyses on novel transgenic animals, I am studying the biology of gut-specific vagal sensory neurons.

Monalee Saha, PhD

Research Fellow 

I am interested in mapping out the signaling pathway involved in the regulation of neurogenesis in the adult ENS. I am interested in studying the role of aberrant metabolic and genetic conditions on the maintenance of the adult ENS. I am also working on characterizing the adult enteric neural stem cells from human tissues.

Shriya Bakhshi

Undergraduate

I am a Junior Undergraduate student pursuing a double major in Neuroscience and Psychology. I joined K-Lab because I am interested in the lab’s work on understanding the development and neurogenesis of the ENS. I am also particularly interested in the use of neurogenic cell subpopulations for treatments of various neurodegenerative diseases. In my free time, I like being outdoors, traveling, and reading books. 

Ananta Srivastava

Undergraduate

I am a first-year undergraduate neuroscience student at Hopkins, and I am originally from Chicago, Illinois. Before joining the K-lab, my past research focused on the protein alpha-synuclein in Parkinson's Disease. In my free time, I love playing with my dog or binge-watching as many Netflix shows as possible.  

LAB ALUMNI

Zhuolun Wang

 

Currently: Graduate Student at Johns Hopkins Pathobiology Program